Description

3-(5-Methylthiophen-2-Yl)-N'-[(E)-Phenylmethylidene]-1H-Pyrazole-5-Carbohydrazide CAS NO 1284266-56-3 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and anti-inflammatory drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• API Development: Employed in the research and development of new Active Pharmaceutical Ingredients (APIs), particularly for potential anti-cancer and anti-inflammatory applications.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study enzyme function and protein interactions in biological systems.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs supporting outsourced pharmaceutical R&D and production.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	3-(5-Methylthiophen-2-Yl)-N'-[(E)-Phenylmethylidene]-1H-Pyrazole-5-Carbohydrazide
CAS No.	1284266-56-3
Molecular Formula	C16H14N4OS
Molecular Weight	310.37 g/mol
Synonyms	3-(5-Methyl-2-thienyl)-N-[(1E)-2-phenylethenyl]-1H-pyrazole-5-carbohydrazide; (E)-3-(5-Methylthiophen-2-yl)-N'-(benzylidene)-1H-pyrazole-5-carbohydrazide; N'-Benzylidene-3-(5-methyl-2-thienyl)-1H-pyrazole-5-carbohydrazide; 3-(5-Methyl-2-thienyl)-1H-pyrazole-5-carboxylic acid, 2-(phenylmethylene)hydrazide; 1284266-56-3; Pyrazole-thiophene carbohydrazide derivative
EINECS	Contact for details

Quality Control

Our 3-(5-Methylthiophen-2-Yl)-N'-[(E)-Phenylmethylidene]-1H-Pyrazole-5-Carbohydrazide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.