Description

9-Bromo-2,3-Diiodo-5,6-Dihydrobenzo[F]Imidazo[1,2-D][1,4]Oxazepine is a high-purity, multi-halogenated heterocyclic compound that serves as a critical advanced pharmaceutical intermediate for the synthesis of novel active ingredients. Its complex fused-ring structure, featuring bromine and iodine substituents, makes it a valuable versatile building block for medicinal chemistry research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogen functionalities into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its reactive halogen sites.
• Agrochemical Development: Serves as a building block for creating new active ingredients for crop protection products.
• Material Science: Potential monomer or precursor for the development of specialty polymers and organic electronic materials.
• Chemical Biology: Can be utilized as a probe or linker in bioconjugation and target identification studies.
• Cross-Coupling Reactions: The bromo and iodo groups make it an excellent substrate for palladium-catalyzed Suzuki, Sonogashira, and Buchwald-Hartwig reactions.

Basic Information

Product Name	9-Bromo-2,3-Diiodo-5,6-Dihydrobenzo[F]Imidazo[1,2-D][1,4]Oxazepine
CAS No.	1282516-68-0
Molecular Formula	C12H5BrI2N2O
Molecular Weight	526.89 g/mol
Synonyms	9-Bromo-2,3-diiodo-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepine; Benzo[f]imidazo[1,2-d][1,4]oxazepine, 9-bromo-2,3-diiodo-5,6-dihydro-; 1282516-68-0; 9-Br-2,3-I2-DH-BIO; Bromo-diiodo-dihydrobenzoimidazoxazepine; 5,6-Dihydro-9-bromo-2,3-diiodobenzo[f]imidazo[1,2-d][1,4]oxazepine
EINECS	Contact for details

Quality Control

Our 9-Bromo-2,3-Diiodo-5,6-Dihydrobenzo[F]Imidazo[1,2-D][1,4]Oxazepine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity confirmation, and impurity profiles. Our quality systems are designed to support cGMP compliance for advanced intermediate production, ensuring traceability and documentation for regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.