Description

Griseofulvin-D3 is a deuterium-labeled analog of the antifungal antibiotic griseofulvin, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity stable isotope-labeled compound is essential for ensuring accuracy and reliability in mass spectrometry-based analyses, such as LC-MS/MS, by correcting for variations in sample preparation and instrument response. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors who require precise quantification of griseofulvin in complex matrices.

Application

• Internal Standard for Bioanalysis: Primary use as a deuterated internal standard for the accurate quantification of griseofulvin in pharmacokinetic, toxicokinetic, and bioequivalence studies.
• Pharmaceutical R&D: Employed in method development and validation for drug metabolism and pharmacokinetics (DMPK) research.
• Clinical Research: Used in clinical trial sample analysis to measure drug concentration levels in plasma, serum, or other biological fluids with high precision.
• Forensic & Anti-Doping Analysis: Supports reliable detection and quantification of griseofulvin in forensic toxicology and sports doping control.
• Veterinary Medicine Research: Applied in studies investigating the pharmacokinetics of griseofulvin in animals.
• Environmental & Food Safety Testing: Can be utilized in advanced analytical methods to detect trace levels of antifungal residues.

Basic Information

Product Name	Griseofulvin-D3
CAS No.	1279033-22-5
Molecular Formula	C17H14D3ClO6
Molecular Weight	~359.78 g/mol
Synonyms	(2S,6'R)-7-Chloro-2',4,6-trimethoxy-6'-(methyl-d3)-spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione; Griseofulvin (methyl-d3); Griseofulvin-d3; Deuterated Griseofulvin; Griseofulvin Internal Standard; Griseofulvin (D3)
EINECS	Contact for details

Quality Control

Our Griseofulvin-D3 is manufactured under strict quality control protocols to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity by HPLC, and confirmation of structure. We adhere to relevant industry standards for stable isotope-labeled compounds to guarantee reliable performance and traceability in your critical assays.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.