Description

Chlorotrianisene-D9 (Trimethoxy-D9) is a high-purity, deuterated analog of the synthetic estrogen chlorotrianisene, specifically labeled with nine deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical results. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and analytical testing facilities engaged in method development, pharmacokinetic studies, and quality control for hormone-related compounds.

Application

• Primary use as an Internal Standard (IS) for the quantification of chlorotrianisene and related compounds in biological matrices via LC-MS/MS and GC-MS.
• Critical component in pharmacokinetic and bioanalytical studies to determine drug concentration, metabolism, and excretion profiles.
• Method development and validation in regulatory-compliant analytical laboratories (FDA, EMA) for drug safety and efficacy testing.
• Use in clinical research for the accurate measurement of estrogenic compounds in patient samples.
• Quality control and assurance applications within pharmaceutical manufacturing to monitor active pharmaceutical ingredient (API) purity and stability.
• Research tool in metabolomics and forensic toxicology for the precise identification and quantification of steroid hormones.

Basic Information

Product Name	Chlorotrianisene-D9 (Trimethoxy-D9)
CAS No.	1276197-26-2
Molecular Formula	C23H16D9ClO3
Molecular Weight	~ 381.92 g/mol
Synonyms	1,1',1''-(1-Chloro-1-ethenyl-2-ylidene)tris(4-methoxybenzene)-d9; Chlorotrianisene-d9; Tris(p-anisyl)chloroethylene-d9; TACE-d9; Tri-p-anisylchloroethylene-d9; Deuterated Chlorotrianisene; Chlorotrianisene (Trimethoxy-d9); Trimethoxy-d9 Chlorotrianisene
EINECS	Contact for details

Quality Control

Every batch of Chlorotrianisene-D9 is manufactured and analyzed under strict quality management protocols to ensure exceptional isotopic purity and chemical integrity, suitable for the most demanding analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for isotopic enrichment, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 99.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.