Description

4-(Bromomethyl)-Tetrahydro-2H-Thiopyran is a versatile organosulfur building block featuring a reactive bromomethyl group on a saturated thiopyran ring. This compound is valued for its utility in advanced organic synthesis, particularly in the construction of complex sulfur-containing heterocycles and as a key intermediate in pharmaceutical and agrochemical research. It is primarily sought by research chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for introducing functionalized thiopyran motifs into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting neurological or metabolic disorders where the thiopyran scaffold is pharmacologically relevant.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that incorporate sulfur heterocycles for enhanced biological activity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers or additives for advanced polymers with specific optical or electronic properties.
• Chemical Biology Probes: Utilized to create tagged or modified compounds for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-(Bromomethyl)-Tetrahydro-2H-Thiopyran
CAS No.	1276056-87-1
Molecular Formula	C6H11BrS
Molecular Weight	195.12 g/mol
Synonyms	4-(Bromomethyl)tetrahydro-2H-thiopyran; Tetrahydro-2H-thiopyran-4-ylmethyl bromide; 4-(Bromomethyl)thiane; 4-Bromomethyltetrahydro-2H-thiopyran; Thiopyran, tetrahydro-4-(bromomethyl)-; 4-Bromomethylthiane; 1276056-87-1; 4-Bromomethyl-tetrahydro-thiopyran
EINECS	Contact for details

Quality Control

Every batch of 4-(Bromomethyl)-Tetrahydro-2H-Thiopyran is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP standards where applicable to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.