Description

3-Bromo-8-Chloroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex heterocyclic scaffolds essential for modern chemical research and development. It is primarily utilized by pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, ligands for metal-organic frameworks (MOFs), and specialty polymers.
• Chemical Synthesis: An essential reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other metal-catalyzed transformations to create complex molecular architectures.
• Ligand Synthesis: Used to prepare novel chelating ligands for catalysis and coordination chemistry applications.
• Academic & R&D: A valuable tool for medicinal chemistry programs and exploratory synthetic chemistry in research institutions.

Basic Information

Product Name	3-Bromo-8-Chloroisoquinoline
CAS No.	1276056-76-8
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	8-Chloro-3-bromoisoquinoline; 3-Bromo-8-chloro-isoquinoline; Isoquinoline, 3-bromo-8-chloro-; 1276056-76-8; 3-Br-8-Cl-isoquinoline
EINECS	Contact for details

Quality Control

Our 3-Bromo-8-Chloroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.