Description

3-(Trifluoromethylsulphonyl)Benzyl Alcohol is a high-value fluorinated aromatic building block characterized by the presence of both a benzyl alcohol group and a powerful electron-withdrawing trifluoromethylsulfonyl substituent. This unique structure makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where enhanced lipophilicity, metabolic stability, and electronic properties are required. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the trifluoromethylsulfonyl group for improved biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing stability and performance.
• Polymer Modification: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and durability.
• Ligand & Catalyst Development: Utilized in organometallic chemistry to create sophisticated ligands for catalytic systems.
• Advanced Material Research: A versatile building block in R&D for exploring new fluorinated compounds with tailored electronic characteristics.

Basic Information

Product Name	3-(Trifluoromethylsulphonyl)Benzyl Alcohol
CAS No.	1274903-38-6
Molecular Formula	C8H7F3O3S
Molecular Weight	240.20 g/mol
Synonyms	α-(Trifluoromethylsulfonyl)-m-toluenemethanol; (3-((Trifluoromethyl)sulfonyl)phenyl)methanol; 3-(Trifluoromethanesulfonyl)benzyl Alcohol; 3-(Trifluoromethylsulfonyl)benzenemethanol; Benzenemethanol, 3-[(trifluoromethyl)sulfonyl]-; m-(Trifluoromethylsulfonyl)benzyl Alcohol
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethylsulphonyl)Benzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent quality. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP production for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.