Description

(3Ar,7Ar)-tert-Butyl Hexahydro-1H-Pyrrolo[3,4-C]Pyridine-5(6H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate and chiral building block. This compound is of significant value for its role in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including potential candidates for central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of novel drug candidates, especially for neurological targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing complex heterocyclic libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Serves as a key building block in enantioselective synthesis due to its defined stereochemistry at the 3Ar and 7Ar positions.
• Process Chemistry Development: Employed in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Utilized in universities and research institutes for studying novel organic transformations and catalysis involving bridged bicyclic amine systems.

Basic Information

Product Name	(3Ar,7Ar)-tert-Butyl Hexahydro-1H-Pyrrolo[3,4-C]Pyridine-5(6H)-Carboxylate
CAS No.	1273568-65-2
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	tert-Butyl (3aR,7aR)-octahydro-1H-pyrrolo[3,4-c]pyridine-5-carboxylate; (3aR,7aR)-1,2,3,3a,4,6,7,7a-Octahydro-5H-pyrrolo[3,4-c]pyridine-5-carboxylic acid 1,1-dimethylethyl ester; (3aR,7aR)-Hexahydro-1H-pyrrolo[3,4-c]pyridin-5(6H)-carboxylic acid tert-butyl ester; BOC-(3aR,7aR)-Octahydropyrrolo[3,4-c]pyridine; (R,R)-tert-Butyl octahydro-1H-pyrrolo[3,4-c]pyridine-5-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development under strict quality protocols. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.