Description

(2S)-2-Amino-2-(3-Bromo-4-Chlorophenyl)Ethan-1-Ol CAS NO 1272734-29-8 is a high-purity chiral amino alcohol building block featuring a halogenated aromatic ring system. This compound is a critical intermediate in the synthesis of advanced pharmaceutical active ingredients and fine chemicals, where its defined stereochemistry and functional groups enable precise molecular construction. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and pesticides, leveraging the halogenated phenyl group for bioactivity.
• Ligand and Catalyst Development: Used in asymmetric synthesis as a precursor for chiral ligands and organocatalysts, facilitating enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Biochemical Research: Acts as a building block for designing molecular probes and inhibitors for enzymatic studies and biochemical assays.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with unique optical or electronic properties.

Basic Information

Product Name	(2S)-2-Amino-2-(3-Bromo-4-Chlorophenyl)Ethan-1-Ol
CAS No.	1272734-29-8
Molecular Formula	C8H9BrClNO
Molecular Weight	250.52 g/mol
Synonyms	(S)-2-Amino-2-(3-bromo-4-chlorophenyl)ethanol; (2S)-2-Amino-2-(3-bromo-4-chlorophenyl)ethanol; 1-(3-Bromo-4-chlorophenyl)-2-aminoethanol (S)-; (S)-1-(3-Bromo-4-chlorophenyl)-2-aminoethanol; 2-Amino-2-(3-bromo-4-chlorophenyl)ethan-1-ol (S-enantiomer); (S)-2-Amino-1-(3-bromo-4-chlorophenyl)ethanol; 1272734-29-8; Amino alcohol intermediate 1272734-29-8
EINECS	Contact for details

Quality Control

Our (2S)-2-Amino-2-(3-Bromo-4-Chlorophenyl)Ethan-1-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.