Description

4-(3-Trifluoromethyl-Phenyl)-Thiazole-2-Carbaldehyde is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals and agrochemicals, where the trifluoromethyl and aldehyde functional groups enable precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science: Used in the research and development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Synthesis: The reactive aldehyde group makes it a versatile starting material for constructing complex heterocyclic systems via condensation, cyclization, and cross-coupling reactions.
• Ligand and Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(3-Trifluoromethyl-Phenyl)-Thiazole-2-Carbaldehyde
CAS No.	1272307-59-1
Molecular Formula	C11H6F3NOS
Molecular Weight	257.23 g/mol
Synonyms	2-Formyl-4-[3-(trifluoromethyl)phenyl]thiazole; 4-(3-(Trifluoromethyl)phenyl)thiazole-2-carboxaldehyde; 4-(α,α,α-Trifluoro-m-tolyl)-2-thiazolecarboxaldehyde; 2-Thiazolecarboxaldehyde, 4-[3-(trifluoromethyl)phenyl]-; 4-(3-Trifluoromethylphenyl)thiazole-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our 4-(3-Trifluoromethyl-Phenyl)-Thiazole-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.