Description

2-Amino-2-[3-(Trifluoromethoxy)Phenyl]Ethan-1-Ol is a high-value, fluorinated amino alcohol building block essential for modern organic synthesis. Its unique structure, featuring both an amino group and a trifluoromethoxy aromatic moiety, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily targeted at research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine into complex molecules to enhance their biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides where the trifluoromethoxy group can improve lipophilicity and target binding.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into monomers for advanced polymers, liquid crystals, or specialty coatings to impart unique electronic and surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and biomarkers for diagnostic and research applications.

Basic Information

Product Name	2-Amino-2-[3-(Trifluoromethoxy)Phenyl]Ethan-1-Ol
CAS No.	1270412-45-7
Molecular Formula	C9H10F3NO2
Molecular Weight	221.18 g/mol
Synonyms	2-Amino-2-[3-(trifluoromethoxy)phenyl]ethanol; 1-[3-(Trifluoromethoxy)phenyl]-2-aminoethanol; 2-Amino-1-[3-(trifluoromethoxy)phenyl]ethanol; α-Amino-3-(trifluoromethoxy)benzenemethanol; 3-(Trifluoromethoxy)phenylglycinol; (R/S)-2-Amino-2-(3-trifluoromethoxyphenyl)ethanol; 2-Amino-2-(3-trifluoromethoxyphenyl)ethan-1-ol
EINECS	Contact for details

Quality Control

Our 2-Amino-2-[3-(Trifluoromethoxy)Phenyl]Ethan-1-Ol is manufactured under strict quality management systems. We offer material suitable for research and development purposes, with typical purity levels exceeding 95% (by HPLC). Each batch is characterized by NMR, HPLC, and mass spectrometry to ensure identity and purity. Certificates of Analysis (COA) detailing specific batch results are provided and can be tailored to meet customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.