Description

(4-Pyrrolidin-2-Ylphenyl)Methan-1-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolidine-substituted benzyl alcohol structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities, offering a versatile chiral building block for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) therapeutics, oncology drugs, and other specialized small-molecule therapies.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile building block for constructing novel compound libraries in drug discovery programs, particularly for CNS and oncology targets.
• Asymmetric Synthesis: Utilized in catalytic and stoichiometric asymmetric reactions due to its chiral pyrrolidine moiety, enabling the production of enantiomerically pure compounds.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	(4-Pyrrolidin-2-Ylphenyl)Methan-1-Ol
CAS No.	1270394-82-5
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	2-(4-(Hydroxymethyl)phenyl)pyrrolidine; (4-(2-Pyrrolidinyl)phenyl)methanol; 4-(2-Pyrrolidinyl)benzyl Alcohol; 2-(4-(Hydroxymethyl)phenyl)-1-pyrrolidine; 1-(4-(Hydroxymethyl)phenyl)pyrrolidine-2-carbaldehyde (tautomer); 4-(Pyrrolidin-2-yl)benzyl Alcohol; 2-(4-Hydroxymethylphenyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our (4-Pyrrolidin-2-Ylphenyl)Methan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate production. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.