Description

(1S)-5-Bromo-2,3-dihydro-1H-inden-1-ol is a chiral, brominated indanol derivative that serves as a valuable synthetic intermediate in advanced organic chemistry. Its defined stereochemistry and functionalized aromatic core make it a critical building block for constructing complex molecules with high precision. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides, leveraging its bromine substituent for further functionalization.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and organic electronic materials due to its rigid indane structure.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control.

Basic Information

Product Name	(1S)-5-Bromo-2,3-dihydro-1H-inden-1-ol
CAS No.	1270284-15-5
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	5-Bromo-2,3-dihydro-1H-inden-1-ol, (1S)-; (1S)-5-Bromoindan-1-ol; (S)-5-Bromo-2,3-dihydro-1H-inden-1-ol; 1H-Inden-1-ol, 5-bromo-2,3-dihydro-, (1S)-; (S)-5-Bromoindanol; (1S)-5-Bromo-1-indanol; 1270284-15-5; (S)-(-)-5-Bromoindan-1-ol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chiral intermediates. Each batch of (1S)-5-Bromo-2,3-dihydro-1H-inden-1-ol is characterized and tested to ensure identity, purity, and enantiomeric excess meet exacting standards. A comprehensive Certificate of Analysis (COA) detailing specifications such as chiral purity (HPLC), assay, and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.