Description

1-Chloroethyl 4-Bromoisoindoline-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex bioactive molecules. This compound is valued for its role as a versatile building block, enabling the introduction of both halogenated and ester-functionalized isoindoline scaffolds into target structures. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, process development, and the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing protease inhibitory activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides or fungicides with unique modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	1-Chloroethyl 4-Bromoisoindoline-2-Carboxylate
CAS No.	1269195-03-0
Molecular Formula	C11H11BrClNO2
Molecular Weight	304.57 g/mol
Synonyms	4-Bromo-1-chloroethyl isoindoline-2-carboxylate; 4-Bromo-2-[(1-chloroethoxy)carbonyl]isoindoline; 1-Chloroethyl 4-bromo-2,3-dihydro-1H-isoindole-2-carboxylate; 4-Bromoisoindoline-2-carboxylic acid 1-chloroethyl ester; 2-Carboxy-4-bromoisoindoline 1-chloroethyl ester; (1-Chloroethoxy)carbonyl-4-bromoisoindoline; 1269195-03-0
EINECS	Contact for details

Quality Control

Our 1-Chloroethyl 4-Bromoisoindoline-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.