Description

5-Bromo-7-Methyl-1,2-Dihydroisoquinolin-1-One is a high-purity, synthetically valuable heterocyclic building block. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns for constructing novel isoquinolinone-based scaffolds.
• Agrochemical Development: Acts as a building block for creating new pesticides and herbicides with specific modes of action.
• Organic Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for introducing complex molecular architectures.
• Chemical Biology: Utilized in the development of molecular probes and tool compounds for studying biological pathways.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	5-Bromo-7-Methyl-1,2-Dihydroisoquinolin-1-One
CAS No.	1268521-92-1
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	5-Bromo-7-methyl-1H-isoquinolin-1-one; 5-Bromo-7-methylisoquinolin-1(2H)-one; 1,2-Dihydro-5-bromo-7-methylisoquinolin-1-one; 5-Bromo-7-methyl-1,2-dihydroisoquinolin-1-one; 7-Methyl-5-bromo-1,2-dihydroisoquinolin-1-one; 5-Bromo-7-methyl-1(2H)-isoquinolinone
EINECS	Contact for details

Quality Control

Our 5-Bromo-7-Methyl-1,2-Dihydroisoquinolin-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.