Description

6-(2-Methyl-1-Oxo-2-Propen-1-Yl)-6-Azabicyclo[3.2.0]Heptan-7-One is a specialized bicyclic lactam derivative, recognized as a key advanced pharmaceutical intermediate (API) and a valuable synthon in complex organic synthesis. Its unique fused ring structure containing both an azabicyclo[3.2.0]heptane core and a reactive α,β-unsaturated carbonyl moiety makes it a critical building block for medicinal chemistry research and process development. This high-purity compound is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and library synthesis due to its reactive handles for further functionalization.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for active pharmaceutical ingredients (APIs) at pilot and commercial scales.
• Agrochemical Synthesis: Acts as a precursor in the manufacture of advanced crop protection agents with complex stereochemistry.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Academic & Institutional Research: A valuable compound for methodological studies in organic synthesis, including cycloaddition reactions and heterocycle formation.

Basic Information

Product Name	6-(2-Methyl-1-Oxo-2-Propen-1-Yl)-6-Azabicyclo[3.2.0]Heptan-7-One
CAS No.	1267624-16-7
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	6-(2-Methylacryloyl)-6-azabicyclo[3.2.0]heptan-7-one; 6-Azabicyclo[3.2.0]heptan-7-one, 6-(2-methyl-1-oxo-2-propen-1-yl)-; 6-(2-Methyl-1-oxoprop-2-en-1-yl)-6-azabicyclo[3.2.0]heptan-7-one; 6-(Methacryloyl)-6-azabicyclo[3.2.0]heptan-7-one; Bicyclic Lactam Methacrylate Derivative; API Intermediate 1267624-16-7
EINECS	Contact for details

Quality Control

Our 6-(2-Methyl-1-Oxo-2-Propen-1-Yl)-6-Azabicyclo[3.2.0]Heptan-7-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and cGMP intermediate applications. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, residual solvents, and physical characteristics are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere if prolonged storage is anticipated to minimize potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.