Description

9,9-Dimethyl-2,3,6,7,8,9-Hexahydro-[1,4]Dioxino[2,3-G]Isoquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused-ring heterocyclic structure. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active pharmaceutical ingredients (APIs) with specific biological activities. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) agents, receptor modulators, and other therapeutic small molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for neurological and psychiatric disorders.
• Organic Synthesis Building Block: Used in complex multi-step syntheses to construct intricate molecular architectures for research and development.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Ligand and Receptor Probe Development: Utilized in the creation of specific ligands for studying biological pathways and receptor functions.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high-purity, complex heterocyclic cores.
• Academic and Industrial R&D: A valuable reagent for methodological development and exploratory chemistry in both academic and corporate laboratories.

Basic Information

Product Name	9,9-Dimethyl-2,3,6,7,8,9-Hexahydro-[1,4]Dioxino[2,3-G]Isoquinoline
CAS No.	1267409-40-4
Molecular Formula	C₁₃H₁₇NO₂
Molecular Weight	219.28 g/mol
Synonyms	9,9-Dimethyl-2,3,6,7,8,9-hexahydro-1,4-dioxino[2,3-g]isoquinoline; 1,4-Dioxino[2,3-g]isoquinoline, 2,3,6,7,8,9-hexahydro-9,9-dimethyl-; 9,9-Dimethylhexahydro-1,4-dioxino[2,3-g]isoquinoline; DMDHIQ; Advanced Isoquinoline Derivative; Fused Dioxane-Isoquinoline Intermediate
EINECS	Contact for details

Quality Control

Our 9,9-Dimethyl-2,3,6,7,8,9-Hexahydro-[1,4]Dioxino[2,3-G]Isoquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as verified by advanced analytical techniques (HPLC, GC, NMR). Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.