Description

5-(5-Chlorothiophen-2-Yl)Isoxazol-3-Amine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring both isoxazole and chlorothiophene moieties, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the chlorothiophene and isoxazole rings contribute to biological activity and environmental stability.
• Material Science Research: Acts as a precursor for the synthesis of functionalized polymers, liquid crystals, or organic electronic materials due to its conjugated system and potential for further functionalization.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	5-(5-Chlorothiophen-2-Yl)Isoxazol-3-Amine
CAS No.	1267318-33-1
Molecular Formula	C7H5ClN2OS
Molecular Weight	200.64 g/mol
Synonyms	3-Amino-5-(5-chloro-2-thienyl)isoxazole; 5-(5-Chloro-2-thienyl)-3-isoxazolamine; 5-(5-Chlorothiophen-2-yl)-1,2-oxazol-3-amine; 5-(5-Chloro-2-thienyl)isoxazol-3-amine; 5-(5-Chlorothiophen-2-yl)isoxazol-3-ylamine; (5-Chlorothiophen-2-yl)isoxazol-3-amine; 1267318-33-1; 5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylamine
EINECS	Contact for details

Quality Control

Every batch of 5-(5-Chlorothiophen-2-Yl)Isoxazol-3-Amine is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our standard quality commitment ensures the material meets the stringent requirements for research and scale-up activities in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.