Description

5,7,8-Trimethoxy-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline is a high-purity, synthetically derived tetrahydroisoquinoline alkaloid derivative. This compound is a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex alkaloid-based drug candidates targeting neurological and cardiovascular systems.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new bioactive molecules.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create more complex heterocyclic compounds for various applications.
• Biochemical Research: Investigated for its potential biological activity and interaction with specific enzymes or receptors.

Basic Information

Item	Details
Product Name	5,7,8-Trimethoxy-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1267282-60-9
Molecular Formula	C₁₄H₂₁NO₃
Molecular Weight	251.32 g/mol
Synonyms	4,4-Dimethyl-5,7,8-trimethoxy-1,2,3,4-tetrahydroisoquinoline; 5,7,8-Trimethoxy-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline; 4,4-Dimethyl-5,7,8-trimethoxytetrahydroisoquinoline; 1,2,3,4-Tetrahydro-5,7,8-trimethoxy-4,4-dimethylisoquinoline; TMTHIQ; Trimethoxytetrahydroisoquinoline derivative
EINECS	Contact for details

Quality Control

Our 5,7,8-Trimethoxy-4,4-Dimethyl-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.