Description

6-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is a high-purity, protected indazole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile halogenated scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable building blocks for drug discovery programs and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive iodine handle for cross-coupling reactions.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and target identification.
• Material Science: A potential monomer or precursor for advanced organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis organizations (CSOs) and CDMOs producing client-specific compounds.

Basic Information

Product Name	6-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole
CAS No.	1266386-30-4
Molecular Formula	C₁₂H₁₃IN₂O
Molecular Weight	328.15 g/mol
Synonyms	6-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole; 1-(Oxan-2-yl)-6-iodo-1H-indazole; 6-Iodo-1-(tetrahydropyran-2-yl)-1H-indazole; 6-Iodo-1-(THP)-1H-indazole; 1-(THP)-6-iodoindazole; 6-Iodo-1-(2-tetrahydropyranyl)-1H-indazole; 1H-Indazole, 6-iodo-1-(tetrahydro-2H-pyran-2-yl)-; CAS 1266386-30-4
EINECS	Contact for details

Quality Control

Our 6-Iodo-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Indazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by advanced analytical techniques including HPLC, NMR, and MS. We are committed to supplying material that meets the stringent requirements for research and development use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.