Description

5-Bromo-3-((S)-1-Methylpyrrolidin-3-Yl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate featuring a chiral, substituted indole scaffold. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of targeted small molecule therapeutics. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the creation of novel drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its chiral pyrrolidine-substituted indole core.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Probe Synthesis: Utilized in the creation of chemical probes for studying biological pathways and protein function in academic and industrial research.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.

Basic Information

Item	Detail
Product Name	5-Bromo-3-((S)-1-Methylpyrrolidin-3-Yl)-1H-Indole
CAS No.	1266317-80-9
Molecular Formula	C13H15BrN2
Molecular Weight	279.18 g/mol
Synonyms	(S)-5-Bromo-3-(1-methylpyrrolidin-3-yl)-1H-indole; 5-Bromo-3-[(3S)-1-methyl-3-pyrrolidinyl]-1H-indole; 1H-Indole, 5-bromo-3-[(3S)-1-methyl-3-pyrrolidinyl]-; 1266317-80-9; (S)-5-Bromo-3-(1-methyl-3-pyrrolidinyl)indole; 5-Bromo-3-((S)-1-methylpyrrolidin-3-yl)indole
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-((S)-1-Methylpyrrolidin-3-Yl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.