Description

2-Propylthiobarbituric-D7 Acid is a stable isotope-labeled analog of 2-propylthiobarbituric acid, where seven hydrogen atoms are replaced by deuterium. This compound is of critical importance as a high-purity internal standard for quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is primarily needed by analytical laboratories, pharmaceutical R&D teams, and forensic toxicologists for method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS: Essential for the precise quantification of barbiturate analogs and related metabolites in complex biological matrices.
• Pharmaceutical Research: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of parent compounds.
• Forensic Toxicology: Provides definitive reference material for the accurate analysis of barbiturates in forensic casework.
• Clinical Diagnostics: Supports the development and validation of high-sensitivity assays for therapeutic drug monitoring.
• Biochemical Research: Serves as a tracer in mechanistic studies involving barbiturate-related biochemical pathways.
• Regulatory Compliance Testing: Enables laboratories to meet stringent data quality requirements for regulatory submissions (e.g., FDA, EMA).

Basic Information

Product Name	2-Propylthiobarbituric-D7 Acid
CAS No.	1265919-33-2
Molecular Formula	C7D7H2N2O2S
Molecular Weight	~203.26 g/mol
Synonyms	5-(2-Propyl)-2-thiobarbituric acid-d7; 2-Thiobarbituric acid, 5-(1-methylpropyl)-, d7; Deuterated 2-Propylthiobarbituric Acid; 5-(1-Methylpropyl)-2-thiobarbituric acid-d7; 2-Propyl-2-thiobarbituric acid-d7; 5-Propyl-2-thiobarbituric acid-d7; Stable Isotope Labeled Barbiturate; Internal Standard for Barbiturates-d7
EINECS	Contact for details

Quality Control

Every batch of 2-Propylthiobarbituric-D7 Acid is produced and tested under strict quality management systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical methods (NMR, HPLC, MS) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.