Description

Taurolithocholic Acid-D5 Sodium Salt is a high-purity, deuterium-labeled internal standard critical for advanced analytical research. This compound is specifically designed for the precise quantification of bile acids in complex biological matrices using mass spectrometry. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, diagnostic, and life science sectors, enabling accurate pharmacokinetic studies and biomarker analysis.

Application

• Mass Spectrometry Internal Standard: Primary use as a stable isotope-labeled internal standard for the LC-MS/MS quantification of taurolithocholic acid and related bile acids.
• Pharmacokinetic & Metabolic Studies: Enables accurate tracking of bile acid metabolism, distribution, and excretion in drug development and disease research.
• Clinical Diagnostics: Used in the development and validation of diagnostic assays for liver function, cholestasis, and other metabolic disorders.
• Biomarker Research: Facilitates the precise measurement of bile acid profiles as potential biomarkers in various physiological and pathological conditions.
• Quality Control & Method Development: Serves as a reference material in analytical method development, validation, and routine quality control in pharmaceutical analysis.

Basic Information

Product Name	Taurolithocholic Acid-D5 Sodium Salt
CAS No.	1265476-97-8
Molecular Formula	C₂₆H₄₀D₅NNaO₆S
Molecular Weight	525.73 g/mol
Synonyms	Sodium Taurolithocholate-d5; 3α-Hydroxy-5β-cholan-24-oyltaurine-d5 Sodium Salt; TLC-d5 Sodium Salt; Taurolithocholate-d5 Sodium; Deuterated Taurolithocholic Acid Sodium Salt; 3α-Hydroxy-5β-cholanic acid-24-d5 taurine conjugate sodium salt; (3α,5β)-3-Hydroxy-24-d5-cholan-24-oyltaurine Sodium Salt
EINECS	Contact for details

Quality Control

Every batch of Taurolithocholic Acid-D5 Sodium Salt is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure exceptional isotopic purity and chemical identity. Our quality assurance protocol includes advanced techniques like NMR and mass spectrometry to confirm deuteration level and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and analytical results is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98.0 atom % D
Chemical Purity	≥ 95.0% (by HPLC)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.