Description

S-4-Oxide-4-Hydroxy-2,6-Bis[4-(Trifluoromethyl)Phenyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin is a sophisticated organophosphorus compound featuring a unique dinaphthodioxaphosphepin core structure substituted with trifluoromethylphenyl groups. This compound matters as a high-value chemical intermediate, prized for its structural complexity and the electronic properties imparted by the trifluoromethyl groups, which are crucial in advanced material science and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for applications such as ligand synthesis, catalysis, and the development of novel functional molecules.

Application

• As a key chiral ligand or precursor in asymmetric catalysis for pharmaceutical synthesis.
• As a specialized intermediate in the research and development of novel active pharmaceutical ingredients (APIs).
• In the synthesis of advanced materials, such as organic semiconductors or metal-organic frameworks (MOFs), where its rigid, bulky structure can influence material properties.
• For use in agrochemical research for creating new crop protection agents with enhanced efficacy.
• As a reference standard or building block in academic and industrial research exploring new organophosphorus chemistry.
• Potential use in the development of flame retardants or plasticizers with specific performance characteristics.

Basic Information

Product Name	S-4-Oxide-4-Hydroxy-2,6-Bis[4-(Trifluoromethyl)Phenyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin
CAS No.	1264573-23-0
Molecular Formula	C38H20F6O4P
Molecular Weight	676.53 g/mol
Synonyms	4-Hydroxy-2,6-bis[4-(trifluoromethyl)phenyl]dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin 4-oxide; Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin, 4-hydroxy-2,6-bis[4-(trifluoromethyl)phenyl]-, 4-oxide; S-4-Oxide form; Chiral phosphine oxide ligand precursor; Trifluoromethyl-substituted dioxaphosphepin.
EINECS	Contact for details

Quality Control

Our S-4-Oxide-4-Hydroxy-2,6-Bis[4-(Trifluoromethyl)Phenyl]-Dinaphtho[2,1-D:1',2'-F][1,3,2]Dioxaphosphepin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, NMR, and MS for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.