Description

7-Chloro-1H-Indole-2-Carbonitrile is a versatile and high-value heterocyclic building block in organic synthesis. This compound is critical for the development of novel pharmaceuticals and advanced materials due to its reactive nitrile and chloro-substituted indole core. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Acts as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce the indole moiety into more complex structures.
• Bioconjugation & Probe Development: Useful for creating fluorescent probes or affinity labels for biochemical and diagnostic applications.

Basic Information

Product Name	7-Chloro-1H-Indole-2-Carbonitrile
CAS No.	1264481-38-0
Molecular Formula	C9H5ClN2
Molecular Weight	176.60 g/mol
Synonyms	7-Chloro-1H-indole-2-carbonitrile; 7-Chloroindole-2-carbonitrile; 2-Cyano-7-chloro-1H-indole; 1H-Indole-2-carbonitrile, 7-chloro-; 7-Chloro-2-cyanoindole
EINECS	Contact for details

Quality Control

Our 7-Chloro-1H-Indole-2-Carbonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. We provide comprehensive analytical data including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.