Description

1-Bromo-4-Chloro-5-Fluoro-2-Iodobenzene is a high-value, multi-halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides with enhanced activity and selectivity.
• Material Science: Serves as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and liquid crystals (LCs).
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Stille) to introduce halogenated aryl groups into complex molecular architectures.
• Ligand Preparation: Useful for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Fluorine Chemistry: The presence of fluorine makes it valuable for creating compounds with improved metabolic stability and membrane permeability in drug discovery.

Basic Information

Product Name	1-Bromo-4-Chloro-5-Fluoro-2-Iodobenzene
CAS No.	1263377-64-5
Molecular Formula	C6H2BrClFI
Molecular Weight	335.34 g/mol
Synonyms	4-Bromo-1-Chloro-2-Fluoro-5-Iodobenzene; 2-Iodo-4-Bromo-1-Chloro-5-Fluorobenzene; 1-Bromo-4-chloro-5-fluoro-2-iodo-benzene; Benzene, 1-bromo-4-chloro-5-fluoro-2-iodo-; 1263377-64-5; BCFI-Benzene (abbrev.)
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Chloro-5-Fluoro-2-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling should be performed under subdued lighting or in amber glass containers when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.