Description

3-Bromo-5-Chlorobenzenethiol is a high-purity organosulfur building block characterized by its reactive thiol (-SH) group and halogen substituents. This compound is essential for advanced organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and functional materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and specialty chemical industries for constructing complex sulfur-containing molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those containing aryl thioether or disulfide linkages.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the thiol group enables unique modes of action.
• Ligand and Catalyst Preparation: Serves as a precursor for metal-chelating ligands in catalysis and material science applications.
• Polymer Modification: Employed to introduce thiol functional groups into polymer backbones for cross-linking or to alter material properties.
• Chemical Research: A versatile reagent in academic and industrial research for studying nucleophilic aromatic substitution and palladium-catalyzed coupling reactions.
• Material Science: Used in the development of self-assembled monolayers (SAMs) and organic electronic materials.

Basic Information

Product Name	3-Bromo-5-Chlorobenzenethiol
CAS No.	1263376-19-7
Molecular Formula	C6H4BrClS
Molecular Weight	223.52 g/mol
Synonyms	3-Bromo-5-chlorobenzenethiol; 3-Bromo-5-chlorothiophenol; 5-Chloro-3-bromobenzenethiol; 1-Bromo-3-chloro-5-mercaptobenzene; Benzenethiol, 3-bromo-5-chloro-; (3-Bromo-5-chlorophenyl)thiol
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chlorobenzenethiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide a Certificate of Analysis (COA) with every shipment, detailing purity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. Keep the container in a cool, dry, well-ventilated place away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.