Description

3-(1-(3-Oxo-8-Azabicyclo[3.2.1]Octan-8-Yl)Ethyl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex bicyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, where precise chemical architecture is critical for biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially in neurology and psychiatry.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the production of Active Pharmaceutical Ingredients (APIs) that incorporate the 8-azabicyclo[3.2.1]octane (tropane) moiety.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	3-(1-(3-Oxo-8-Azabicyclo[3.2.1]Octan-8-Yl)Ethyl)Benzonitrile
CAS No.	1263286-48-1
Molecular Formula	C16H18N2O
Molecular Weight	254.33 g/mol
Synonyms	8-Azabicyclo[3.2.1]octan-3-one, 8-[1-(3-cyanophenyl)ethyl]-; 3-[1-(3-Oxo-8-azabicyclo[3.2.1]oct-8-yl)ethyl]benzonitrile; 3-(1-(3-Oxo-8-azabicyclo[3.2.1]octan-8-yl)ethyl)benzonitrile; Tropane-3-one derivative; 8-[1-(3-Cyanophenyl)ethyl]-8-azabicyclo[3.2.1]octan-3-one
EINECS	Contact for details

Quality Control

Our 3-(1-(3-Oxo-8-Azabicyclo[3.2.1]Octan-8-Yl)Ethyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.