Description

4-Thiazolecarboxylic Acid, 2-(Hydroxymethyl)-, 1,1-Dimethylethyl Ester is a high-purity, protected thiazole derivative serving as a critical synthetic intermediate. This compound is valued for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides that incorporate the thiazole moiety for enhanced bioactivity.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes, enzyme inhibitors, and other tools for studying biological systems.
• Material Science Research: Employed in the development of advanced organic materials, including ligands for catalysis and components for electronic materials.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.
• Academic Research: Used in university and institutional laboratories for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	4-Thiazolecarboxylic Acid, 2-(Hydroxymethyl)-, 1,1-Dimethylethyl Ester
CAS No.	1263282-18-3
Molecular Formula	C9H13NO3S
Molecular Weight	215.27 g/mol
Synonyms	tert-Butyl 2-(hydroxymethyl)thiazole-4-carboxylate; 2-(Hydroxymethyl)-4-thiazolecarboxylic Acid 1,1-Dimethylethyl Ester; 4-Thiazolecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester; 2-Hydroxymethyl-thiazole-4-carboxylic acid tert-butyl ester; (2-Hydroxymethyl-thiazol-4-yl)-carboxylic acid tert-butyl ester; tert-Butyl 2-(hydroxymethyl)-1,3-thiazole-4-carboxylate; 1263282-18-3
EINECS	Contact for details

Quality Control

Our 4-Thiazolecarboxylic Acid, 2-(Hydroxymethyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.