Description

5-Methanesulfonyl-3-Methyl-2,3-Dihydro-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indoline scaffold functionalized with a methanesulfonyl group. This compound is of significant value in modern organic synthesis, particularly for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex molecules with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Serves as a core structural motif for developing new pesticides and herbicides with enhanced efficacy and selectivity.
• Chemical Synthesis Building Block: Used in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its reactive sulfonyl group.
• Academic & R&D Laboratories: Employed in methodological research and the discovery of new synthetic pathways involving indole derivatives.
• Material Science Precursor: Potential use in the synthesis of specialized organic compounds for advanced material applications.

Basic Information

Product Name	5-Methanesulfonyl-3-Methyl-2,3-Dihydro-1H-Indole
CAS No.	1263281-98-6
Molecular Formula	C11H13NO2S
Molecular Weight	223.29 g/mol
Synonyms	3-Methyl-5-(methylsulfonyl)-2,3-dihydro-1H-indole; 5-(Methylsulfonyl)-3-methylindoline; 1H-Indole, 2,3-dihydro-5-(methylsulfonyl)-3-methyl-; 3-Methyl-5-methanesulfonylindoline; 5-Methanesulfonyl-3-methylindoline
EINECS	Contact for details

Quality Control

Our 5-Methanesulfonyl-3-Methyl-2,3-Dihydro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.