Description

3-Chloroisoquinoline-7-Carboxylic Acid is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, which allows for selective derivatization at both the carboxylic acid and halogenated positions, enabling the construction of complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating novel chelating ligands used in catalysis and material science.
• Functional Material Development: Incorporated into the design of organic semiconductors, fluorescent probes, and metal-organic frameworks (MOFs).
• Chemical Biology: Employed as a molecular scaffold for designing enzyme inhibitors and biological probes in biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) specializing in complex heterocyclic chemistry.

Basic Information

Product Name	3-Chloroisoquinoline-7-Carboxylic Acid
CAS No.	1263207-80-2
Molecular Formula	C10H6ClNO2
Molecular Weight	207.61 g/mol
Synonyms	7-Isoquinolinecarboxylic acid, 3-chloro-; 3-Chloro-7-isoquinolinecarboxylic acid; 3-Chloro-7-carboxyisoquinoline; 3-Chloroisoquinoline-7-carboxylic acid; 1263207-80-2; 3-Cl-IQC-OH
EINECS	Contact for details

Quality Control

Every batch of 3-Chloroisoquinoline-7-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your critical research and development projects. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed HPLC purity, NMR, and MS data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.