Description

16-Mercaptohexadecylamine Hydrochloride is a high-purity, bifunctional organic compound featuring both a terminal thiol (-SH) and a primary amine (-NH2) group, rendered as a hydrochloride salt for enhanced stability. This unique structure makes it a critical building block for creating self-assembled monolayers (SAMs) and functionalized surfaces with precise chemical control. It is essential for researchers and manufacturers in nanotechnology, surface science, and advanced material synthesis who require reliable, high-quality linkers for gold-thiol chemistry and subsequent amine-mediated conjugation.

Application

• Surface Functionalization & Self-Assembled Monolayers (SAMs): The thiol group provides robust attachment to gold, silver, and other metal surfaces, while the amine terminus allows for further covalent coupling of biomolecules, polymers, or nanoparticles.
• Biosensor and Diagnostic Device Fabrication: Used to create stable, functional interfaces on sensor chips for immobilizing antibodies, DNA probes, or enzymes, enhancing sensitivity and specificity.
• Nanoparticle Capping and Stabilization: Acts as a ligand to functionalize and stabilize metallic (e.g., gold, quantum dots) or magnetic nanoparticles, imparting water solubility and bio-conjugation capability.
• Corrosion Inhibition and Surface Modification: Forms protective monolayers on metal surfaces to prevent oxidation and corrosion, or to modify surface properties like wettability and adhesion.
• Polymer and Dendrimer Synthesis: Serves as a versatile monomer or initiator in the synthesis of specialty polymers, dendrimers, and cross-linked networks via thiol-ene or amine-reactive chemistries.
• Chromatography and Separation Media: Can be immobilized on silica or polymer supports to create stationary phases for affinity chromatography or solid-phase extraction.

Basic Information

Product Name	16-Mercaptohexadecylamine Hydrochloride
CAS No.	1263190-70-0
Molecular Formula	C16H36ClNS
Molecular Weight	309.98 g/mol
Synonyms	16-Amino-1-hexadecanethiol hydrochloride; 16-Mercaptohexadecan-1-amine hydrochloride; 1-Amino-16-mercaptohexadecane hydrochloride; Hexadecyl-16-thiolamine hydrochloride; 16-Sulfanylhexadecylamine hydrochloride; C16 Thiol-Amine HCl; 16-MHDA HCl; 16-Mercaptohexadecylammonium chloride
EINECS	Contact for details

Quality Control

Our 16-Mercaptohexadecylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and FT-IR for structural confirmation, and titration for chloride content. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or light will degrade product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Titration)	97.0 - 103.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.