Description

(2-Amino-5-Fluorophenyl)Dimethylphosphine Oxide is a specialized organophosphorus compound featuring a unique combination of an amino group, a fluorine substituent, and a phosphine oxide moiety. This structure makes it a valuable building block and key intermediate in advanced synthetic chemistry, particularly for constructing complex molecular architectures. It is primarily utilized by pharmaceutical researchers and agrochemical developers engaged in the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand in Catalysis: The phosphine oxide group can be utilized in the design of ligands for transition metal catalysis, enabling challenging chemical transformations.
• Material Science Research: Used in the development of specialty polymers and functional materials where the incorporation of fluorine and phosphorus imparts specific properties like flame retardancy or stability.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying biological processes and enzyme mechanisms.

Basic Information

Product Name	(2-Amino-5-Fluorophenyl)Dimethylphosphine Oxide
CAS No.	1263178-53-5
Molecular Formula	C8H11FNOP
Molecular Weight	187.15 g/mol
Synonyms	Dimethyl(2-amino-5-fluorophenyl)phosphine oxide; 2-Amino-5-fluorophenyldimethylphosphine oxide; 5-Fluoro-2-aminophenyldimethylphosphine oxide; (2-Amino-5-fluorophenyl)dimethylphosphine oxide; N-(5-Fluoro-2-(dimethylphosphinyl)phenyl)amine; (5-Fluoro-2-aminophenyl)dimethylphosphine oxide
EINECS	Contact for details

Quality Control

Every batch of (2-Amino-5-Fluorophenyl)Dimethylphosphine Oxide is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.