Description

(3-Iodo-Indazol-1-Yl)-Acetic Acid Ethyl Ester is a high-purity, functionalized indazole derivative of significant interest in advanced organic synthesis. This compound serves as a critical building block for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drug candidates, especially kinase inhibitors and other enzyme modulators.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Agrochemical Development: Serves as a versatile synthon for creating novel active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocyclic chemistry.
• Academic Research: Used in university and institutional labs for methodological development and the discovery of new chemical reactions involving halogenated heterocycles.

Basic Information

Product Name	(3-Iodo-Indazol-1-Yl)-Acetic Acid Ethyl Ester
CAS No.	1262500-86-6
Molecular Formula	C11H11IN2O2
Molecular Weight	330.12 g/mol
Synonyms	Ethyl (3-iodo-1H-indazol-1-yl)acetate; 1H-Indazol-1-acetic acid, 3-iodo-, ethyl ester; Ethyl 2-(3-iodo-1H-indazol-1-yl)acetate; (3-Iodo-1H-indazol-1-yl)acetic Acid Ethyl Ester; 3-Iodo-1H-indazole-1-acetic acid ethyl ester; AI3-72925; ZINC000103074715; BCP31933
EINECS	Contact for details

Quality Control

Our (3-Iodo-Indazol-1-Yl)-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.