Description

5-(2-Carboxythiophene-4-Yl)-3-Chlorophenol is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a thiophene carboxylic acid moiety with a chlorinated phenol, enabling precise chemical modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drug candidates, particularly in therapeutic areas requiring complex heterocyclic scaffolds.
• Agrochemical Research: Serves as a versatile precursor in the synthesis of new-generation herbicides, fungicides, and insecticides with tailored activity profiles.
• Material Science: Used in the research and development of advanced organic electronic materials, such as conductive polymers and organic semiconductors.
• Ligand Synthesis: Employed in the preparation of specialized chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Acts as a core structure for creating fluorescent tags or bioactive probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, complex aromatic compounds.

Basic Information

Product Name	5-(2-Carboxythiophene-4-Yl)-3-Chlorophenol
CAS No.	1262003-03-1
Molecular Formula	C12H7ClO3S
Molecular Weight	266.70 g/mol
Synonyms	3-Chloro-5-(2-carboxythiophen-4-yl)phenol; 4-(3-Chloro-5-hydroxyphenyl)thiophene-2-carboxylic Acid; 5-(3-Chloro-5-hydroxyphenyl)thiophene-2-carboxylic Acid; 5-(2-Carboxy-4-thienyl)-3-chlorophenol; 3-Chloro-5-(2-thiophenecarboxylic acid-4-yl)phenol; 4-(5-Chloro-3-hydroxyphenyl)-2-thiophenecarboxylic acid; CAS 1262003-03-1
EINECS	Contact for details

Quality Control

Our 5-(2-Carboxythiophene-4-Yl)-3-Chlorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.