Description

5-(2-Carboxythiophene-4-Yl)-3-Fluorophenol is a high-purity, multi-functional organic building block designed for advanced chemical synthesis. This compound matters because it combines a fluorophenol moiety with a carboxythiophene group, offering unique reactivity for constructing complex molecular architectures. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients, particularly as a key intermediate in medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialty polymers and organic electronic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile scaffold for exploring new chemical reactions and creating compound libraries for high-throughput screening.

Basic Information

Product Name	5-(2-Carboxythiophene-4-Yl)-3-Fluorophenol
CAS No.	1261936-09-7
Molecular Formula	C12H7FO3S
Molecular Weight	250.25 g/mol
Synonyms	3-Fluoro-5-(4-thienyl-2-carboxyl)phenol; 5-(4-Carboxy-2-thienyl)-3-fluorophenol; 3-Fluoro-5-(2-carboxy-4-thienyl)phenol; 4-(3-Fluoro-5-hydroxyphenyl)thiophene-2-carboxylic acid; 5-(2-Carboxy-4-thienyl)-3-fluorophenol; 3-Fluoro-5-(thiophene-2-carboxylic acid-4-yl)phenol; 1261936-09-7
EINECS	Contact for details

Quality Control

Our 5-(2-Carboxythiophene-4-Yl)-3-Fluorophenol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.