Description

2-(2-Carboxythiophene-4-Yl)Phenol is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines phenolic and thiophene carboxylic acid functionalities, enabling its use in creating complex target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as drug discovery and the development of specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Serves as a precursor in the design and synthesis of new-generation herbicides and fungicides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and advanced organic frameworks (MOFs/COFs) due to its electron-rich thiophene core.
• Ligand and Catalyst Development: Employed as a starting material for synthesizing complex chelating ligands used in homogeneous catalysis and metal-organic chemistry.
• Dye and Pigment Intermediate: Functions as a building block for creating specialized dyes and organic pigments with specific light-absorption properties.
• Academic and Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic chemistry projects.

Basic Information

Product Name	2-(2-Carboxythiophene-4-Yl)Phenol
CAS No.	1261896-15-4
Molecular Formula	C11H8O3S
Molecular Weight	220.24 g/mol
Synonyms	4-Hydroxy-3-(2-thiophenecarboxylic acid)benzene; 2-(4-Hydroxyphenyl)thiophene-2-carboxylic acid; Phenol, 2-(2-carboxy-4-thienyl)-; 2-(2-Carboxy-4-thienyl)phenol; 4-(2-Carboxythiophen-4-yl)phenol; 2-(2-Carboxythiophen-4-yl)phenol; 2-(4-Hydroxyphenyl)-2-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-(2-Carboxythiophene-4-Yl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your compliance needs in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.