Description

Ethyl 4-Azaindole-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the azaindole class of heterocyclic compounds. Its core value lies in serving as a critical building block for the synthesis of novel, small-molecule drug candidates targeting a range of therapeutic areas. This compound is essential for research and development chemists in the pharmaceutical and biotechnology industries, particularly those focused on kinase inhibitors and other targeted therapies. Its defined structure and purity are paramount for ensuring reproducible results in complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries via parallel synthesis and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound Development: Serves as a core structure for developing probes and inhibitors used in enzymatic assays and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process development for client drug discovery programs.
• Academic Research: Utilized in university and institutional labs for investigating novel heterocyclic chemistry and new therapeutic modalities.

Basic Information

Product Name	Ethyl 4-Azaindole-6-Carboxylate
CAS No.	1261885-66-8
Molecular Formula	C10H10N2O2
Molecular Weight	190.20 g/mol
Synonyms	Ethyl 1H-Pyrrolo[3,2-b]pyridine-6-carboxylate; 4-Azaindole-6-carboxylic acid ethyl ester; 6-(Ethoxycarbonyl)-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic acid, ethyl ester; Ethyl 1H-7-azaindole-6-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Azaindole-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.