Description

7-(Difluoromethoxy)Isoquinoline is a high-value fluorinated isoquinoline derivative, a key building block in modern pharmaceutical and agrochemical research. Its unique structure, featuring a difluoromethoxy substituent, is critical for modulating the biological activity, metabolic stability, and lipophilicity of target molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate this privileged scaffold into novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of potential drug candidates targeting various therapeutic areas, including oncology, CNS disorders, and infectious diseases.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the difluoromethoxy group can enhance bioavailability and environmental stability.
• Chemical Biology Probe: Acts as a versatile building block for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Employed in the synthesis of advanced organic materials, such as ligands for catalysis or components for organic electronics.
• Process Chemistry & Scale-Up: A critical raw material for process optimization and the commercial-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	7-(Difluoromethoxy)Isoquinoline
CAS No.	1261787-58-9
Molecular Formula	C₁₀H₇F₂NO
Molecular Weight	195.17 g/mol
Synonyms	7-(Difluoromethoxy)isoquinoline; Isoquinoline, 7-(difluoromethoxy)-; 1261787-58-9; 7-Difluoromethoxyisoquinoline; 7-(Difluoromethoxy)-isoquinoline; 7-(Difluoromethoxy) isoquinoline; 7-(Difluoromethoxy)isoquinoline (CAS 1261787-58-9)
EINECS	Contact for details

Quality Control

Every batch of 7-(Difluoromethoxy)Isoquinoline is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with each shipment to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.