Description

7-(Difluoromethyl)Quinoline is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role in introducing the difluoromethyl group, a key bioisostere that can significantly modulate the physicochemical and metabolic properties of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Key pharmaceutical intermediate in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Versatile fluorinated building block for constructing complex molecules in agrochemical research, where the difluoromethyl group can enhance biological activity and environmental stability.
• Precursor in material science for developing advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters or charge-transport layers.
• Used in academic and industrial R&D for method development in fluorination chemistry and cross-coupling reactions.
• Intermediate for synthesizing specialty chemicals and ligands for catalysis.

Basic Information

Product Name	7-(Difluoromethyl)Quinoline
CAS No.	1261728-71-5
Molecular Formula	C₁₀H₇F₂N
Molecular Weight	179.17 g/mol
Synonyms	7-(Difluoromethyl)quinoline; Quinoline, 7-(difluoromethyl)-; 7-Difluoromethylquinoline; 7-(Difluoromethyl)chinolin; 7-Difluoromethyl-chinolin
EINECS	Contact for details

Quality Control

Our 7-(Difluoromethyl)Quinoline is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with each shipment to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.