Description

(2-Bromo-3-Iodophenyl)Methanol is a versatile halogenated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive benzylic alcohol and two distinct halogen handles (bromine and iodine) for selective cross-coupling and functionalization reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized phosphine or N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Material Science Research: Building block for creating functionalized monomers or additives for advanced polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine and bromine substituents allow for sequential, site-selective Suzuki, Stille, or Sonogashira coupling reactions to construct complex biaryl systems.
• Chemical Biology Probes: Useful in synthesizing tagged molecules or photoaffinity labels for proteomics and target identification studies.

Basic Information

Product Name	(2-Bromo-3-Iodophenyl)Methanol
CAS No.	1261644-21-6
Molecular Formula	C7H6BrIO
Molecular Weight	312.93 g/mol
Synonyms	2-Bromo-3-iodobenzyl alcohol; (2-Bromo-3-iodophenyl)methanol; 1-(2-Bromo-3-iodophenyl)methanol; Benzenemethanol, 2-bromo-3-iodo-; α-(2-Bromo-3-iodophenyl)methanol; 3-Iodo-2-bromobenzyl alcohol
EINECS	Contact for details

Quality Control

Our (2-Bromo-3-Iodophenyl)Methanol is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under amber glass or foil-wrapped containers to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.