Description

(2-Iodo-5-Nitro-Phenyl)-Methanol is a versatile halogenated nitroaromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of an iodine substituent, a nitro group, and a benzylic alcohol functional group, enabling a range of selective chemical transformations. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the iodine atom facilitates efficient cross-coupling reactions to introduce diverse heterocycles.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the preparation of functionalized monomers for advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: The aryl iodide moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings.

Basic Information

Product Name	(2-Iodo-5-Nitro-Phenyl)-Methanol
CAS No.	1261611-57-7
Molecular Formula	C7H6INO3
Molecular Weight	295.04 g/mol
Synonyms	2-Iodo-5-nitrobenzyl alcohol; (2-Iodo-5-nitrophenyl)methanol; 5-Nitro-2-iodobenzyl alcohol; 1-Iodo-2-(hydroxymethyl)-4-nitrobenzene; α-Hydroxy-2-iodo-5-nitrotoluene; 2-Iodo-α-hydroxy-5-nitrotoluene; Benzenemethanol, 2-iodo-5-nitro-
EINECS	Contact for details

Quality Control

Our (2-Iodo-5-Nitro-Phenyl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature, the container should be amber-colored or kept in secondary opaque packaging. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.