Description

1-Bromo-3-Chloro-5-(Difluoromethyl)Benzene is a high-purity, multi-functional halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluoromethylphenyl moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogen and difluoromethyl groups modulate biological activity.
• Material Science: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Organic Electronics: Employed in the synthesis of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromo and chloro substituents.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	1-Bromo-3-Chloro-5-(Difluoromethyl)Benzene
CAS No.	1261580-23-7
Molecular Formula	C7H4BrClF2
Molecular Weight	241.46 g/mol
Synonyms	3-Bromo-5-Chlorobenzyl Difluoride; 5-Bromo-3-Chlorobenzyl Difluoride; 1-Bromo-3-chloro-5-(difluoromethyl)benzene; 3-Chloro-5-bromo-alpha,α-difluorotoluene; (3-Bromo-5-chlorophenyl)difluoromethane; Benzene, 1-bromo-3-chloro-5-(difluoromethyl)-; 1261580-23-7
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-5-(Difluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical properties is provided with every shipment to guarantee supply consistency and traceability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.