Description

(2-Chloro-5-Trifluoromethoxy-Phenyl)-Methanol is a high-value fluorinated aromatic building block, distinguished by its unique trifluoromethoxy and chlorophenyl substituents. This compound is critical for introducing specific steric and electronic properties into advanced molecular architectures, enabling the development of novel materials and active ingredients. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry and crop protection product synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the research and production of specialty electronic materials, where its aromatic and fluorinated structure contributes to desired dielectric and luminescent properties.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating high-performance polymers with enhanced chemical resistance and thermal stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct complex, multi-functional organic molecules for various R&D applications.

Basic Information

Product Name	(2-Chloro-5-Trifluoromethoxy-Phenyl)-Methanol
CAS No.	1261483-31-1
Molecular Formula	C8H6ClF3O2
Molecular Weight	226.58 g/mol
Synonyms	2-Chloro-5-(trifluoromethoxy)benzyl alcohol; (2-Chloro-5-(trifluoromethoxy)phenyl)methanol; 1-(2-Chloro-5-(trifluoromethoxy)phenyl)methanol; α-Hydroxymethyl-2-chloro-5-trifluoromethoxybenzene; 2-Chloro-α-(hydroxymethyl)-5-(trifluoromethoxy)benzene; Benzyl alcohol, 2-chloro-5-(trifluoromethoxy)-; 2-Chloro-5-trifluoromethoxybenzyl alcohol
EINECS	Contact for details

Quality Control

Our (2-Chloro-5-Trifluoromethoxy-Phenyl)-Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.