Description

Dehydroepiandrosterone-[D6] is a high-purity, stable isotope-labeled analog of the endogenous steroid hormone Dehydroepiandrosterone (DHEA), specifically deuterated at six positions. This compound is an essential reference standard and internal standard for the precise quantification of DHEA in complex biological matrices using advanced analytical techniques like LC-MS/MS and GC-MS. It is primarily utilized by research institutions, pharmaceutical companies, and clinical diagnostic laboratories engaged in endocrinology research, drug metabolism studies, and the development of accurate bioanalytical assays.

Application

• Quantitative Bioanalysis: Serves as a critical internal standard for the accurate and precise measurement of endogenous DHEA levels in serum, plasma, and tissue samples via mass spectrometry.
• Endocrinology & Steroid Research: Enables detailed studies of adrenal function, steroidogenesis pathways, and the role of DHEA in aging, metabolism, and immune response.
• Pharmacokinetics & Drug Development: Used in ADME (Absorption, Distribution, Metabolism, Excretion) studies to track the metabolism of deuterated drug candidates or to normalize data in assays involving DHEA pathways.
• Clinical Diagnostics: Supports the development and validation of robust clinical diagnostic tests for hormonal disorders, ensuring high accuracy and reproducibility.
• Forensic Toxicology: Aids in the confirmatory analysis of steroid hormones in forensic investigations.
• Quality Control & Method Validation: Acts as a certified reference material for calibrating instruments and validating analytical methods in compliance with GLP and ISO 17025 standards.

Basic Information

Product Name	Dehydroepiandrosterone-[D6]
CAS No.	1261254-39-0
Molecular Formula	C19H22D6O2
Molecular Weight	294.45 g/mol
Synonyms	DHEA-d6; 3β-Hydroxy-5-androsten-17-one-d6; 5-Androsten-3β-ol-17-one-d6; Dehydroisoandrosterone-d6; Prasterone-d6; (3β)-3-Hydroxyandrost-5-en-17-one-d6; Androstenolone-d6; 17-Ketoandrost-5-en-3β-ol-d6
EINECS	Contact for details

Quality Control

Every batch of Dehydroepiandrosterone-[D6] CAS 1261254-39-0 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including HPLC for chemical purity and MS for isotopic enrichment verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for identity, purity, and solvent content. Our quality commitment ensures reliability for your most demanding research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99.0 atom % D
Chemical Purity (by HPLC)	≥ 98.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.