Description

tert-Butyl 4-((5-Bromothiophene-2-Sulfonamido)Methyl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfonamide-linked heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a key building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially those targeting enzyme inhibition.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable piperidine and bromothiophene groups.
• Protease Inhibitor Development: The sulfonamide moiety makes it a valuable scaffold for developing inhibitors of various proteases and other enzymes.
• Chemical Biology Probes: Serves as a starting material for creating molecular probes to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring complex heterocyclic chemistry.
• Library Synthesis: Used in the generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	tert-Butyl 4-((5-Bromothiophene-2-Sulfonamido)Methyl)Piperidine-1-Carboxylate
CAS No.	1261232-69-2
Molecular Formula	C16H23BrN2O4S2
Molecular Weight	451.40 g/mol
Synonyms	1-Boc-4-((5-Bromothiophene-2-Sulfonamido)Methyl)Piperidine; 1-(tert-Butoxycarbonyl)-4-[[(5-bromo-2-thienyl)sulfonyl]amino]methyl]piperidine; 4-[[(5-Bromothiophen-2-yl)sulfonyl]amino]methyl]piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(((5-bromothiophene-2-yl)sulfonamido)methyl)piperidine-1-carboxylate; N-[(1-Boc-4-piperidinyl)methyl]-5-bromothiophene-2-sulfonamide; 5-Bromo-N-[(1-(tert-butoxycarbonyl)-4-piperidinyl)methyl]-2-thiophenesulfonamide; BOC-4-((5-Bromothiophene-2-Sulfonamido)Methyl)Piperidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-((5-Bromothiophene-2-Sulfonamido)Methyl)Piperidine-1-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, NMR, MS) to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.