Description

Thiophene-2-Sulfonic Acid Pyrrolidin-3-Ylamide Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small molecule therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for creating targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns for developing new therapeutic agents.
• Protease Inhibitor Development: The sulfonamide and amide functionalities make it a valuable scaffold for designing enzyme inhibitors.
• Chemical Biology Probes: Serves as a precursor for creating tool compounds to study biological processes and target validation.
• Custom Synthesis: Employed in contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Library Synthesis: Used to generate diverse compound libraries for high-throughput screening (HTS) in drug discovery.

Basic Information

Item	Detail
Product Name	Thiophene-2-Sulfonic Acid Pyrrolidin-3-Ylamide Hydrochloride
CAS No.	1261232-64-7
Molecular Formula	C9H13ClN2O2S2
Molecular Weight	280.79 g/mol
Synonyms	3-[(Thiophen-2-ylsulfonyl)amino]pyrrolidine hydrochloride; 1-(Thiophene-2-sulfonyl)pyrrolidin-3-amine hydrochloride; Pyrrolidin-3-amine, 1-(2-thienylsulfonyl)-, hydrochloride; Thiophene-2-sulfonamide, N-(3-aminopyrrolidin-1-yl)-, hydrochloride; T2SPAH; 1261232-64-7; CAS 1261232-64-7
EINECS	Contact for details

Quality Control

Our Thiophene-2-Sulfonic Acid Pyrrolidin-3-Ylamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.