Description

Methyl 7-Fluoro-2-Oxoindoline-5-Carboxylate, 97% is a high-purity fluorinated oxindole derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate) in modern synthetic chemistry. Its value lies in providing a versatile, high-quality building block for the research and development of novel bioactive molecules, particularly in the pharmaceutical sector. This compound is essential for medicinal chemists and process development scientists working in pharmaceutical R&D, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Intermediate in the development of new fluorinated pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Chemical Process Development: Serves as a standard or starting material for scaling up synthetic routes in pilot plants and manufacturing.
• Academic & Institutional Research: Utilized in universities and research institutes for exploring novel heterocyclic chemistry and fluorination effects.
• Custom Synthesis & Contract Manufacturing: A requested intermediate for bespoke chemical synthesis services catering to the pharmaceutical and biotechnology industries.

Basic Information

Product Name	Methyl 7-Fluoro-2-Oxoindoline-5-Carboxylate, 97%
CAS No.	1260879-22-8
Molecular Formula	C10H8FNO3
Molecular Weight	209.18 g/mol
Synonyms	Methyl 7-fluoro-2-oxo-2,3-dihydro-1H-indole-5-carboxylate; 5-Carbomethoxy-7-fluorooxindole; 7-Fluoro-2-oxoindoline-5-carboxylic acid methyl ester; 7-Fluoro-5-(methoxycarbonyl)indolin-2-one; Methyl 7-fluoro-2-oxo-1,2-dihydroindole-5-carboxylate; 7-Fluorooxindole-5-carboxylic acid methyl ester; 1H-Indole-5-carboxylic acid, 7-fluoro-2,3-dihydro-2-oxo-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 7-Fluoro-2-Oxoindoline-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure the specified purity of 97% (min.) and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	97.0% min.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.