Description

6-Bromo-8-Fluoroisoquinolin-3-Amine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated isoquinoline scaffold, which provides a versatile platform for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its halogenated heterocyclic structure.
• Material Science: Serves as a building block for organic semiconductors, ligands for catalysis, and specialty polymers.
• Medicinal Chemistry SAR Studies: The bromo and fluoro substituents allow for strategic derivatization to explore structure-activity relationships.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for target identification and validation.
• Custom Synthesis: An essential starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	6-Bromo-8-Fluoroisoquinolin-3-Amine
CAS No.	1260815-69-7
Molecular Formula	C9H6BrFN2
Molecular Weight	241.06 g/mol
Synonyms	3-Amino-6-bromo-8-fluoroisoquinoline; 6-Bromo-8-fluoro-3-isoquinolinamine; 8-Fluoro-6-bromoisoquinolin-3-amine; 1260815-69-7; 6-Bromo-8-fluoroisoquinolin-3-ylamine; AI3-63173; SCHEMBL21849627; ZINC000253894977
EINECS	Contact for details

Quality Control

Our 6-Bromo-8-Fluoroisoquinolin-3-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF for moisture content, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.