Description

Ethyl 7-Bromo-3,4-Dihydroisoquinoline-2(1H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the dihydroisoquinoline class of heterocyclic compounds. This compound is a critical building block in modern organic synthesis, valued for its versatile reactivity and bromine substituent, which enables further functionalization. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and other transformations to construct more elaborate molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds.
• Agrochemical Development: Potential use in the synthesis of novel crop protection agents and pesticides.
• Academic & Industrial R&D: Employed in chemical research for developing new synthetic methodologies and exploring novel heterocyclic chemistry.

Basic Information

Product Name	Ethyl 7-Bromo-3,4-Dihydroisoquinoline-2(1H)-Carboxylate
CAS No.	1260804-19-0
Molecular Formula	C₁₂H₁₂BrNO₂
Molecular Weight	282.13 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid ethyl ester; Ethyl 7-bromo-1,2,3,4-tetrahydroisoquinoline-2-carboxylate; 2-Carbethoxy-7-bromo-1,2,3,4-tetrahydroisoquinoline; 7-Bromo-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester; 1260804-19-0; Ethyl 7-bromodihydroisoquinoline-2(1H)-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 7-Bromo-3,4-Dihydroisoquinoline-2(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.